Metal-free arylation of thiols with diaryliodonium salts has been {developed|created}. The application of a {strong|powerful|robust|sturdy} organic base ena-bles the C–S bond formation {under|below|beneath} mild and experimentally {simple|easy|straightforward|basic|uncomplicated|very simple} {conditions|circumstances|situations}. The {method|technique|approach|strategy|system|process} {allows|enables|permits|makes it possible for} for the synthesis of aryl sulfides containing a broad {range of|selection of|array of} aryl groups from an array of thiols, {including|such as|which includes|like} aryl, heteroaryl, and alkyl ones. The mechanism {of the|from the|in the|on the|with the|of your} reaction was studied by DFT calculations, demonstrating {that is|that’s|which is|that is certainly|that is definitely|that may be} follows the inner sphere pathway involv-ing the incipient formation of Ar2I(SR) intermediate, followed by the reductive elimination. 1300746-79-5 web 1337880-39-3 site PMID:23800738
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