A one-pot transformation of biaryl dicarboxylic acids to (NH)-phenanthridinone derivatives {based|primarily based} on a Curtius rearrangement and subsequent {basic|fundamental|simple|standard} hydrolysis was {developed|created}. This {method|technique|approach|strategy|system|process} {is also|can also be} applicable for the preparation of optically active amide-functionalized [7]helicene-like molecules. {Furthermore|Moreover|In addition|Additionally}, aza[5]helicene derivatives {with a|having a|using a} phosphate moiety {were|had been|have been} isolated as a {product|item|solution} {of the|from the|in the|on the|with the|of your} Curtius rearrangement step {in the|within the|inside the} case of substrates that bear chalcogen atoms. The stereostructures {of these|of those} {products|goods|items|merchandise|solutions}, revealed by X-ray diffraction {analysis|evaluation}, {suggested|recommended} that chalcogen-bonding and pnictogen-bonding interactions {might|may|may well|may possibly|could|could possibly} contribute to their stabilization. The configurational stability {of the|from the|in the|on the|with the|of your} helicene-like molecules and their chiroptical properties {were|had been|have been} {further|additional} investigated. 1H-Benzotriazole-1-carboxaldehyde Purity 1243361-03-6 Purity PMID:27102143
Headquartered in New Jersey, USA, ChemScence is a global leading manufacturer and supplier of building blocks and fine research chemicals. We now have branches in Sweden and India. Our mission is to pave the way for drug discovery by providing the most innovative chemicals with the highest-level quality for a reasonable price.
Our Catalog Products
We deliver an extensive portfolio of products, including Building Blocks,Catalysts&Ligands,Synthetic Reagents,Material Science and ADC Linkers&Protac,.ChemScene now have over 600000 Building Blocks & Intermediates in our catalog and more than 70000 of them are in stock.
For details, please refer to the ChemScene website:https://www.chemscene.com