Visible light promoted chemo-selective metal {free|totally free|free of charge|cost-free|absolutely free|no cost} hydrogenation of activated double bond has been {achieved|accomplished} {via|by way of|through|by means of} photoredox catalysis. Eosin Y has proved to an {efficient|effective} catalyst for the {effective|efficient|successful|powerful|productive|helpful} reduction of C-C double bonds of isatins, oxindoles and maleimides {under|below|beneath} visible light. The {method|technique|approach|strategy|system|process} worked {efficiently|effectively} {without|with out|without having|with no|devoid of|without the need of} the {aid|help} of any external reductants. Commercially viable DIPEA has been employed as a sacrificial electron donor and {it’s|it is} in-situ generated cationic radical acts as reductant {in this|within this} transformation. The {method|technique|approach|strategy|system|process} proved {to be|to become} {practical|sensible} as a broad {range|variety} of substrates containing activated double bond {were|had been|have been} {easily|effortlessly|very easily|simply|quickly|conveniently} {reduced|decreased|lowered}. The {method|technique|approach|strategy|system|process} proved {to be|to become} scalable on a gram scale {and the|and also the|as well as the|along with the|plus the} {reduced|decreased|lowered} {product|item|solution} has been utilized {successfully|effectively} for the {further|additional} synthetic application. The systematic and detailed mechanistic {studies|research} reveal the reductive quenching {of the|from the|in the|on the|with the|of your} photocatalyst by the activated double bond. 702699-84-1 structure 5-Fluoro-6-hydroxynicotinic acid Chemical name PMID:25040798
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