{4|four},{6|six},10-Trihydroxy-1,{4|four},{6|six},10-tetraazaadamantane (TAAD) has been shown to {form|type|kind} a {stable|steady} Fe(IV) {complex|complicated} {having|getting|possessing|obtaining} a diamantane cage structure, in which the metal center is coordinated by {three|3} oxygen atoms {of the|from the|in the|on the|with the|of your} deprotonated ligand. The {complex|complicated} was characterized by X-ray, HRMS, NMR, FT-IR, Mössbauer spectroscopy and DFT calculations, which supported d4 configuration of iron. The Fe(IV)-TAAD {complex|complicated} showed {excellent|superb|outstanding|exceptional|great|fantastic} {performance|overall performance|efficiency|functionality} in dioxygen activation {under|below|beneath} mild {conditions|circumstances|situations} serving as a mimetic {of the|from the|in the|on the|with the|of your} thiol oxidase enzyme. The nucleophilicity {of the|from the|in the|on the|with the|of your} bridge-head nitrogen atom in TAAD {provides|offers|gives|supplies|delivers} a {straightforward|simple} way for conjugation of Fe(IV)-TAAD complexes to {various|numerous|different|a variety of|several|many} functional molecules. {Using|Utilizing|Making use of|Employing|Working with|Applying} this {approach|method|strategy}, steroidal and peptide molecules {having|getting|possessing|obtaining} an iron(IV) label {have been|happen to be|have already been} {prepared|ready} for {the first|the very first|the initial} time. Also, the Fe(IV)-TAAD {complex|complicated} was covalently bounded to a polystyrene matrix {and the|and also the|as well as the|along with the|plus the} resulting material was shown to serve as a heterogeneous catalyst for aerobic oxidation of thiols to disulfides. 5-Nitro-1H-pyrazole-3-carbonitrile structure Buy5-Fluoro-1H-1,2,4-triazole PMID:24458656
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