{Here|Right here} we report a facile and {efficient|effective} triphosgene-assisted one-pot conversion of aldehydes/ketones into nitriles/amides. The triphosgene, a {kind|type|sort} of phosgene {alternative|option}, containing {both|each} ester linkage and chloromethyl units, {easily|effortlessly|very easily|simply|quickly|conveniently} reacts with oximes for the preparation of nitriles/amides. {However|Nevertheless|Nonetheless|Even so|On the other hand|Having said that}, the reaction of oximes with triphosgene {can’t|cannot|can not} {fully|totally|completely} convert corresponding nitriles/amides {due to|because of|as a result of|on account of|resulting from|as a consequence of} hydrolysis of oximes to aldehydes or ketones. Our protocol tandem proceeds smoothly {without|with out|without having|with no|devoid of|without the need of} {the use of|the usage of} organic base and metal catalysts. Diverse functionalized aromatic, aliphatic, and allylic aldehydes/ketones incorporating biomass-derived platform compounds {were|had been|have been} {successfully|effectively} converted to nitriles and amides in {excellent|superb|outstanding|exceptional|great|fantastic} yields. {Compared to|In comparison to|In comparison with|When compared with} step-by-step reaction, this tandem {strategy|technique|method|approach|tactic} is characterized by multi-step reaction in {one|1|a single|one particular} pot, mild reaction {conditions|circumstances|situations}, and fewer by-products. DBCO-acid site Triruthenium Dodecacarbonyl Data Sheet PMID:35991869
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