{In the|Within the|Inside the} manuscript {the first|the very first|the initial} enantioselective dearomative Michael addition {between|in between|among|amongst|involving} α,β-unsaturated aldehydes and 2-nitrobenzofurans realized {under|below|beneath} N-heterocyclic carbene activation has been described. The reaction proceeds {via|by way of|through|by means of} addition of homoenolate to Michael acceptors {leading|top|major} {to the|towards the|for the} formation of biologically {important|essential|crucial|critical|significant|vital} heterocycles with {high|higher} yields and stereoselectivities. Their functionalization {potential|possible|prospective} has been confirmed in {selected|chosen}, diastereoselective transformations. 2,5-Dibromo-4-fluoropyridine Purity Methyl 2-chloroquinazoline-6-carboxylate Chemscene PMID:26446225
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