The {development|improvement} of {straightforward|simple} and {efficient|effective} synthetic {methods|techniques|strategies|approaches|procedures|solutions} toward ring-fused heteroaromatic polymers with {attractive|appealing|desirable|eye-catching} functionalities has {great|fantastic|excellent|wonderful|good|terrific} significance in {both|each} chemistry and {materials|supplies|components} science. Herein, we {develop|create} a facile cascade C-H-activated polyannulation route {that can|that may|that will|that could|which will|which can} in situ {generate|produce|create} {multiple|numerous|several|a number of|many|various} ring-fused aza-heteroaromatic polymers from readily {available|accessible|obtainable|offered|readily available|out there} monomers in an atom-economical manner. A series of {complex|complicated} polybenzimidazole derivatives with {high|higher} absolute molecular weights of {up to|as much as} 24000 are {efficiently|effectively} {produced|created|made|developed} in {high|higher} yields {within|inside} {2|two} hours. Benefiting from their {unique|distinctive|special|exclusive|exceptional|one of a kind} imidazole-containing ring-fused structures with {multiple|numerous|several|a number of|many|various} aryl pendants, the obtained polymers show {excellent|superb|outstanding|exceptional|great|fantastic} thermal and morphological stability, {good|great|excellent|very good|fantastic|superior} {solution|answer|remedy|resolution|option} processability, {high|higher} refractive index, {small|little|tiny|modest|smaller|compact} chromic dispersion, {as well|also|too|at the same time} as {remarkable|outstanding|exceptional} acid-base-responsive fluorescence. Taking {advantage|benefit} {of the|from the|in the|on the|with the|of your} ratiometric fluorescence response {of the|from the|in the|on the|with the|of your} triphenylamine-substituted heteroaromatic polymer to pH variations, we {successfully|effectively} apply it as a sensitive fluorescence probe for the mapping and quantitative {analysis|evaluation} of intracellular pH {changes|modifications|adjustments|alterations} in {live|reside} cells. {Furthermore|Moreover|In addition|Additionally}, {through|via|by means of|by way of} the {simple|easy|straightforward|basic|uncomplicated|very simple} N-methylation reaction {of the|from the|in the|on the|with the|of your} ring-fused polybenzimidazoles, diverse azonia-containing polyelectrolytes are readily {produced|created|made|developed}, which can {efficiently|effectively} kill cancer cells {via|by way of|through|by means of} the synergistic effects of dark toxicity and photo-toxicity. Buy(1R,2R)-Cyclohexane-1,2-diamine 1842337-34-1 custom synthesis PMID:24318587
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