We present protocols for the {highly|extremely|very|hugely} regioselective hydroxyselenylation and silanoxyselenylation of allylicsilanols. N-(Phenylseleno)phthalimide acts {as the|because the} selenylating agent for {both|each} transformations. {Under|Below|Beneath} {basic|fundamental|simple|standard} {conditions|circumstances|situations}, hydroxyselenylation proceeds with >20:1 regioselectivity, {and the|and also the|as well as the|along with the|plus the} {products|goods|items|merchandise|solutions} are {valuable|beneficial|useful|worthwhile|precious|important} synthons for {further|additional} transformations. We show that the silanol plays a {critical|crucial|vital|essential|important} {role|function|part} in {maintaining|sustaining|preserving|keeping} the yield and regioselectivity of this reaction. Surprisingly, {under|below|beneath} acidic {conditions|circumstances|situations}, the hydroxyselenylation pathway is blocked, and {products|goods|items|merchandise|solutions} of a tethered silanoxyselenylation are exclusive. 1,7-Dibromoheptane site 6-Bromobenzo[d]isothiazole In stock PMID:24282960
Headquartered in New Jersey, USA, ChemScence is a global leading manufacturer and supplier of building blocks and fine research chemicals. We now have branches in Sweden and India. Our mission is to pave the way for drug discovery by providing the most innovative chemicals with the highest-level quality for a reasonable price.
Our Catalog Products
We deliver an extensive portfolio of products, including Building Blocks,Catalysts&Ligands,Synthetic Reagents,Material Science and ADC Linkers&Protac,.ChemScene now have over 600000 Building Blocks & Intermediates in our catalog and more than 70000 of them are in stock.
For details, please refer to the ChemScene website:https://www.chemscene.com