Herein, we describe a chemoenzymatic synthesis {of the|from the|in the|on the|with the|of your} bicyclic fragment of Darunavir. A ketoreductase was identified {using|utilizing|making use of|employing|working with|applying} metagenomic mining to catalyze a…
Liquid chromatography coupled to mass spectrometry {is a|is really a|is actually a|can be a|is often a|is usually a} {key|important|crucial|essential} metabolomics {technology|technologies}. Reversed-phase liquid chromatog-raphy (RPLC) {is very|is extremely|is quite} {widely|extensively|broadly}…
Dearomatized indole derivatives bearing a C3- or C2-stereocenter exist ubiquitously in {natural|all-natural|organic} {products|goods|items|merchandise|solutions} and biologically active molecules. {Despite|Regardless of|In spite of} {remarkable|outstanding|exceptional} advances in their chemical synthesis, stereoselective and regio-divergent…
Concentrated solar plants are promising {solutions|options} for {electricity|electrical energy} production. In these plants, the heat transfer fluid plays {an important|an essential|a crucial|a vital} {role|function|part}, and {finding|discovering|locating|obtaining|acquiring|getting} systems with {good|great|excellent|very good|fantastic|superior}…
The {development|improvement} of {straightforward|simple} and {efficient|effective} synthetic {methods|techniques|strategies|approaches|procedures|solutions} toward ring-fused heteroaromatic polymers with {attractive|appealing|desirable|eye-catching} functionalities has {great|fantastic|excellent|wonderful|good|terrific} significance in {both|each} chemistry and {materials|supplies|components} science. Herein, we {develop|create} a facile cascade…
The encapsulation of chemotherapeutics by biocompatible carrier structures holds {great|fantastic|excellent|wonderful|good|terrific} {promise|guarantee} to preserve their therapeutic activity and favor their delivery to tumor {sites|websites|web sites|internet sites|web-sites|web pages}. To {enhance|improve|boost} the bioavailability…
Multivariate chemical reaction optimization involving catalytic systems {is a|is really a|is actually a|can be a|is often a|is usually a} non-trivial {task|job|activity|process} {due to|because of|as a result of|on account of|resulting from|as…
This {work|function|perform|operate} describes the synthesis and photoluminescence of new heteroleptic mixed-carbene cyclometalated iridium complexes. Complexes are synthesized {via|by way of|through|by means of} a nucleophilic addition cascade reaction with isocyanide-bound precursors.…
Atomic layer deposition (ALD) {allows|enables|permits|makes it possible for} {for a|to get a|for any} {great|fantastic|excellent|wonderful|good|terrific} {level of|degree of|amount of} {control|manage|handle} {over|more than} the thickness and stoichiometry of {materials|supplies|components}. ALD {provides|offers|gives|supplies|delivers} a…
Viral genomes {can be|may be|could be|might be|is often|is usually} compressed into a {near|close to} spherical nanochamber to {form|type|kind} infected particles. {In order to|To be able to|As a way to|In an…