The application of merocyanine photoacids has been previously largely {limited|restricted} to neutral and acidic pH values. {Here|Right here} we introduce {a new|a brand new} merocyanine photoacid with superior pH switching qualities. By {increasing|growing|escalating|rising} the pKa {in the|within the|inside the} dark (pKadark) {and the|and also the|as well as the|along with the|plus the} solubility we {increased|elevated|improved|enhanced} the reversible visible light induced pH jump to {3|three}.{5|five} units. {Moreover|Furthermore|In addition|Additionally}, {it is|it’s|it really is|it truly is|it can be|it is actually} {the first|the very first|the initial} demonstration of a merocyanine photoacid {able to|in a position to} {generate|produce|create} a {significant|substantial|considerable|important} pH drop from a {basic|fundamental|simple|standard} (pH {8|eight}.{3|three}) to an acidic (pH {5|five}.{2|two}) {environment|atmosphere}. 2621932-42-9 custom synthesis 1889290-53-2 manufacturer PMID:24463635
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