The continuous use of chemical fertilizer {affects|impacts} the {environment|atmosphere} and soil fertility. Bio-fertilizer {helps|assists|aids} in safeguarding soil fertility and {reduce|decrease|minimize|lessen|lower|cut down} environmental pollution. This {research|study|analysis|investigation} focuses {on the|around the} optimization of production of bio-fertilizer from watermelon peels. Central Composite {Design|Style|Design and style} (CCD) {under|below|beneath} the Response Surface Methodology (RSM) {of the|from the|in the|on the|with the|of your} {Design|Style|Design and style} {Expert|Professional|Specialist} {software|software program|computer software|application} version {6|six}.0 was {used|utilized|employed|utilised|applied|made use of} to optimize the retention days and water ratio, ({factors|elements|aspects|variables|components|things}), {while|whilst|although|even though|when|though} Nitrogen(N), Phosphorous (P) and potassium (K) {were|had been|have been} the responses. Watermelon peel was blended and fermented for {different|various|distinct|diverse|unique|distinctive} days {based|primarily based} {on the|around the} experimental {design|style|design and style} obtained. The optimum values obtained {after|following|right after|soon after|immediately after|just after} optimization for retention days and water ratio are 20 days and 400 ml respectively, {while|whilst|although|even though|when|though} N. P and K contents are 26.2824, 94.5099 and 0.0005, respectively. {The use of|The usage of} Bio-fertilizer {will be|will probably be|will likely be|is going to be|might be|are going to be} {more|much more|a lot more|far more|additional|extra} economical and safer for farming activities. 2,2′-Bipyrimidine site Exatecan Intermediate 2 structure PMID:24013184
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