We describe that the reduction-cleavable spacer (RCS) containing a nitrobenzene scaffold {can be|may be|could be|might be|is often|is usually} incorporated into a single-stranded DNA sequence to {enable|allow} the {construction|building} of a reduction-responsive DNA architecture with spherical morphology at micrometer scale. The RCS could {allow|permit|enable|let} for the introduction {of the|from the|in the|on the|with the|of your} reduction-responsiveness into {various|numerous|different|a variety of|several|many} functional oligonucleotides {as well|also|too|at the same time} as nucleic acid-based architectures. Trifluoromethanesulfonic acid (silver) Chemscene 1203499-17-5 Chemical name PMID:22943596

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