In living organisms, {many|numerous|several|a lot of|quite a few|lots of} dynamic mechanisms are driven by motor proteins on a wide scale for tasks {including|such as|which includes|like} the assembly of hierarchical structures {at the|in the} nano to micrometre scales and macroscopic movements with hierarchical structures. Such {complicated|complex|difficult} assemblies and sophisticated functions are intriguing for applications in nano and microengineering. {Using|Utilizing|Making use of|Employing|Working with|Applying} motor proteins {may|might|could|may possibly|may well|may perhaps} {enable|allow} multimolecular assembly in artificial systems by reproducing {simple|easy|straightforward|basic|uncomplicated|very simple} molecular movements {using|utilizing|making use of|employing|working with|applying} established {methods|techniques|strategies|approaches|procedures|solutions} {such as|like|including|for example|for instance|which include} motility assays of kinesin and microtubules. {However|Nevertheless|Nonetheless|Even so|On the other hand|Having said that}, {building|developing|creating|constructing} a multimolecular {system|method|program|technique} and {selecting|choosing|picking|deciding on} the target functions are {key|important|crucial|essential} points {to consider|to think about} for {potential|possible|prospective} applications. We use an active matrix consisting of crosslinked microtubules driven by kinesin to agitate microscopic objects {that are|which are|which can be|which might be|that happen to be} not moved by thermal fluctuation, {that is|that’s|which is|that is certainly|that is definitely|that may be}, non-Brownian particles. This {method|technique|approach|strategy|system|process} {may|might|could|may possibly|may well|may perhaps} contribute to {enhance|improve|boost} {various|numerous|different|a variety of|several|many} self-assembly processes for {larger|bigger} objects. The resulting isotropic agitating properties are compared with {those|these} of other agitation {methods|techniques|strategies|approaches|procedures|solutions} {based on|according to|depending on|determined by} external forces exerted by electric motors. The active matrix {may|might|could|may possibly|may well|may perhaps} {provide|offer|supply|give|present|deliver} {a new|a brand new} {type|kind|sort|variety|form} of mesoscopic scale actuator to {perform|carry out|execute} stochastic mechanical agitation. Biotin-PEG3-azide custom synthesis 2-(3-Bromopyridin-4-yl)acetonitrile custom synthesis PMID:24458656
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