Continuous-flowchemistry is emerging as an enabling {technology|technologies} for the synthesis of precisepolymers. {Despite|Regardless of|In spite of} {recent|current} advances {in this|within this} {rapidly|quickly|swiftly} {growing|expanding|developing|increasing} field, there remainsa {need|require|want|need to have|will need|have to have} {for a|to get a|for any} {fundamental|basic} understanding of how fluid dynamics in tubularreactors influence polymerizations. Herein, we report a {comprehensive|complete|extensive} study ofhow laminar flow influences polymer structure and composition. Tracerexperiments coupled with in-line UV-vis spectroscopy demonstrate how viscosity,tubing diameter, and reaction time {affect|impact|have an effect on|influence} the residence time distribution (RTD)of fluid in reactor geometries relevant for continuous-flow polymerizations. Wefound that the breadth {of the|from the|in the|on the|with the|of your} RTD has {strong|powerful|robust|sturdy}, statistical correlations withreaction conversion, polymer molar mass, and dispersity for polymerizationsconducted in continuous flow. These correlations {were|had been|have been} demonstrated to begeneral to {a variety of|a number of|many different|various|a range of|several different} {different|various|distinct|diverse|unique|distinctive} reaction {conditions|circumstances|situations}, monomers, andpolymerization mechanisms. {Additionally|In addition|Furthermore|Moreover|Also|On top of that}, these findings inspired the {design|style|design and style} ofa droplet flow reactor that minimizes the RTD in continuous-flowpolymerizations and enables the continuous production of well-defined polymerat a {rate|price} of 1.{4|four} kg/day. 157327-48-5 structure 1112178-31-0 Purity PMID:23613863
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