The (Z) and (E) isomers of an extended tetraphenylethylene-based chromophore with optimized two-photon induced luminescence properties are separated and functionalized with water-solubilizing pendant polymer groups, {promoting|advertising} their self-assembly in physiological media {in the|within the|inside the} {form of|type of|kind of} {small|little|tiny|modest|smaller|compact}, colloidal {stable|steady} organic nanoparticles. The two resulting fluorescent suspensions are then evaluated as {potential|possible|prospective} two-photon luminescent contrast agents for intravital epifluorescence and two-photon fluorescence microscopy. Comparisons with previously reported {works|functions|operates|performs} involving {similar|comparable|equivalent|related} fluorophores devoid of polymer side chains illustrate the {benefits of|advantages of} the later functionalization {regarding|concerning|relating to|with regards to} the {control|manage|handle} {of the|from the|in the|on the|with the|of your} self-assembly {of the|from the|in the|on the|with the|of your} nano-objects, and {ultimately|in the end|eventually} their biocompatibility towards the imaged organism. Price of 1245647-53-3 6-Bromothiazolo[4,5-b]pyridin-2-amine uses PMID:35954127
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