Product Name :
NM23 Mouse Monoclonal Antibody [13C1]
Predicted band size :
17 kDa
Observed band size :
17/20 kDa
Synonyms:
AWD antibody AWD, drosophila, homolog of antibody GAAD antibody Granzyme A activated DNase antibody Granzyme A-activated DNase antibody GZMA activated DNase antibody Metastasis inhibition factor NM23 antibody NB antibody NBS antibody NDK A antibody 展开
Function :
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3′-5′ exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3′ end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Synthetic peptide within Human NM23 aa 1-50 / 152.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, FC, IF-Cell
Coupling :
unconjugated
Clone number:
13C1
RRID:
AB_3068854
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein A affinity purified.Methyl 2-formyl-6-nitrobenzoate custom synthesis
ELTSA :
Molecular weight :
Predicted band size: 17 kDa
Positive control :
HEK-293 cell lysate, MCF7 cell lysate, Jurkat cell lysate, HeLa cell lysate, HepG2 cell lysate, K-562 cell lysate, A549 cell lysate, Raji cell lysate, NIH/3T3 cell lysate, C6 cell lysate, mouse kidney tissue lysate, mouse liver tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, rat liver tissue lysate, human liver carcinoma tissue, human thyroid tissue, human skin tissue, human breast carcinoma tissue, 293.Nicotinamide riboside (chloride) Chemical name