An {efficient|effective} {strategy|technique|method|approach|tactic} for the synthesis of {large|big|huge|massive|substantial|significant} libraries of conformationnally defined peptides is reported,{using|utilizing|making use of|employing|working with|applying} dynamic combinatorial chemistry as a tool to graft amino acid side chains on a well-ordered 3Dpeptide backbone. Combining rationnally {designed|developed|created|made} scaffolds with combinatorial side chains selectionrepresents an {alternative|option} {method|technique|approach|strategy|system|process} to access peptide libraries for structures {that are|which are|which can be|which might be|that happen to be} not geneticallyencodable. This {method|technique|approach|strategy|system|process} would {allow|permit|enable|let} a breakthrough for the discovery of protein mimetic for unconventionaltargets for which {little|small|tiny} is {known|recognized|identified}. 2-Bromo-6-iodoaniline Chemscene 5458-56-0 uses PMID:23319057
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