Product Name :
NSUN5 Recombinant Rabbit Monoclonal Antibody [PSH05-07]

Predicted band size :
47 kDa

Observed band size :
47 kDa

Synonyms:
FLJ10267 antibody MGC986 antibody NOL1 antibody NOL1-related protein antibody NOL1/NOP2/Sun domain family member 5 antibody NOL1R antibody NOP2/Sun domain family, member 5 antibody NOP2/Sun domain family, member 5A antibody NSUN5 antibody NSUN5_HUMAN antibody 展开

Function :
Putative methyltransferase NSUN5 is an enzyme that in humans is encoded by the NSUN5 gene. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development (By similarity). This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Antibody Type:
Recombinant Rabbit monoclonal Antibody

Immunogen :
Synthetic peptide within human NSUN5 aa 51-100 / 429.

Species reactivity:
Human, Mouse, Rat

Verify application:
WB

Coupling :
unconjugated

Clone number:
PSH05-07

RRID:

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing.352525-25-8 Chemical name Aliquot store at -20℃.3-Methoxy-2,6-dimethyl-aniline structure Avoid repeated freeze / thaw cycles.PMID:33569797

Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
Predicted band size: 47 kDa

Positive control :
HeLa cell lysate, Caco-2 cell lysate, K-562 cell lysate, A431 cell lysate, MEF cell lysate, PC-12 cell lysate, human kidney tissue lysate, mouse kidney tissue lysate, mouse spleen tissue lysate, rat spleen tissue lysate.