The preparation of halogenated benzene-1,{2|two},{3|three},4-tetracarboxylic diimide derivatives is {challenging|difficult} {because of|due to|as a result of} the possibility of competitive incorrect cyclizations and SNAr reactivity. {Here|Right here}, we demonstrate that the direct reaction of benzene-1,{2|two},{3|three},4-tetracarboxylic acids with {primary|main|major|principal|key} amines in acetic acid solvent {successfully|effectively} {provides|offers|gives|supplies|delivers} a {range|variety} of desirable ortho-diimide {products|goods|items|merchandise|solutions} in {good|great|excellent|very good|fantastic|superior} yields. {Furthermore|Moreover|In addition|Additionally}, we demonstrate that sterically {challenging|difficult} N-derivatizations {can be|may be|could be|might be|is often|is usually} readily {achieved|accomplished} {under|below|beneath} microwave reactor {conditions|circumstances|situations}, and that SNAr reactivity is only observed when excess amine is {used|utilized|employed|utilised|applied|made use of}. The halogenated diimides described {here|right here} are {attractive|appealing|desirable|eye-catching} {building|developing|creating|constructing} blocks for organic {materials|supplies|components} chemistry. 89284-85-5 site Cyclopentylhydrazine hydrochloride Chemical name PMID:23805407
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