Nitrogen-13 labeled ammonia ([13N]NH3) has been {used|utilized|employed|utilised|applied|made use of} for myocardial perfusion imaging with Positron Emission Tomography for decades. {Recent|Current} increases to regulatory oversight have led to stricter adherence {Good|Great|Excellent|Very good|Fantastic|Superior} Manufacturing Practice (GMP) to {produce|create|generate|make} this {short|brief|quick} half-life (9.97 min) radiopharmaceutical. This has {increased|elevated|improved|enhanced} production {costs|expenses|fees|charges}. Our cyclotron facility initially {developed|created} amanual GMP production {method|technique|approach|strategy|system|process}, {but it|however it|nevertheless it} was prone to human error. With {increased|elevated|improved|enhanced} {costs|expenses|fees|charges} in {mind|thoughts}, we {developed|created} and validation an Arduino-based device to purifying [13N]NH3 for clinical use. {Construction|Building}, programming, and GMP validation {results|outcomes|final results|benefits} are discussed. The automated {method|technique|approach|strategy|system|process} was {found|discovered|identified|located} to {produce|create|generate|make} equivalent {quality|high quality|top quality|good quality|excellent|high-quality} radiopharmaceutical but was {more|much more|a lot more|far more|additional|extra} reproducible and robust. Boc-NH-PEG2-C2-NH2 Chemscene Bis(triphenylphosphine)dichloronickel site PMID:24202965
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