The conversion processes of sugarcane into direct-consumption sugar and juice are {generating|producing|creating} a tremendous {amount of|quantity of|level of|volume of} waste, the so-called sugarcane bagasse. Biochar preparation is {among|amongst} the {practical|sensible} {solutions|options} aiming to valorize this agrowaste and make it of a {high|higher} added {value|worth} functional material (FM). Herein, we propose a novel zero-waste pathway {where|exactly where} sugarcane bagasse was {first|initial|very first|1st|initially} dispersed {in a|inside a|within a} hydroalcoholic {solution|answer|remedy|resolution|option} {and the|and also the|as well as the|along with the|plus the} dispersion was then ultrasonicated {in order to|to be able to|as a way to|in an effort to|so as to|so that you can} extract {natural|all-natural|organic} {reducing|decreasing|lowering|minimizing} and capping agents. Subsequently, silver and copper ions {were|had been|have been} added {to get|to obtain|to acquire|to have} adsorbed {under|below|beneath} a controlled atmosphere {prior to|before} heat {treatment|therapy|remedy}. The suspension was later filtered {to provide|to supply} (i) Ag/Cu-Ag+/Cu2+-loaded biomass sludge, and (ii) a clear filtrate containing residual metal ions which was microwaved {in order to|to be able to|as a way to|in an effort to|so as to|so that you can} {generate|produce|create} unsupported Ag/Cu nanoparticles (NPs). The {free|totally free|free of charge|cost-free|absolutely free|no cost} Ag/Cu nanoparticles (FM2) {were|had been|have been} tested as anti-kinetoplastid material against two flagellate models namely Leishmania spp and Trypanosoma cruzi. {Free|Totally free|Free of charge|Cost-free|Absolutely free|No cost} Ag/Cu nanoparticles showed the highest leishmanicidal and trypanocidal effects with an IC50 of {2|two}.909 ± 0.051; {3|three}.580 ± 0.016 and {3|three}.020 ± 0.372 ppm for L.donovani, L. amazonensis and Trypanosoma cruzi, respectively. The impregnated biomass was pyrolyzed {to provide|to supply} Ag/Cu-loaded biochar (FM1). The latter exhibited {high|higher} catalytic activity {in the|within the|inside the} total mineralization of methylene blue. The experimental {data|information} followed {the first|the very first|the initial} {and the|and also the|as well as the|along with the|plus the} pseudo-second order {rate|price} laws with apparent mineralization {rate|price} constants K1 45 10-3 min-1 and K2 0.115 g.mg-1.min-1, respectively. To sum up, sugarcane bagasse agrowaste was valorized as a {source|supply} of {natural|all-natural|organic} {reducing|decreasing|lowering|minimizing} agents of metal ions into {free|totally free|free of charge|cost-free|absolutely free|no cost} and biochar-supported metallic nanoparticles. {In this|Within this} way, we combine two {concepts|ideas}: green chemistry and valorization of agrowaste {in a|inside a|within a} {full|complete} zero-waste {process|procedure|method|approach|course of action}, for addressing pollution and neglected tropical {disease|illness} {issues|problems|concerns|troubles|difficulties|challenges}. 5-Amino-3-methylindazole Formula 92220-65-0 Purity PMID:23522542
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