Selective functionalization of allylic C-H bonds into other chemical bonds with Z-selectivity are {among|amongst} {the most|probably the most|essentially the most|one of the most|by far the most} {straightforward|simple} and {attractive|appealing|desirable|eye-catching}, {yet|however|but} {challenging|difficult} transformations. Herein, a transition-metal-free protocol for direct allylic C-H nitrogenation, oxygenation, and carbonation of alkenes by thianthrenation was {developed|created}. This operationally {simple|easy|straightforward|basic|uncomplicated|very simple} protocol {allows|enables|permits|makes it possible for} for the unified allylic C-H amination, esterification, etherification, and arylation of vinyl thiathrenium salts. Notably, the reaction preferably {provides|offers|gives|supplies|delivers} multialkyl substituted allylic amines, esters, and ethers with Z-selectivity. The reaction proceeds {under|below|beneath} mild {conditions|circumstances|situations} with {excellent|superb|outstanding|exceptional|great|fantastic} functional group tolerance and {could be|might be|could possibly be|may be|may very well be} applied to late-stage allylation of {natural|all-natural|organic} {products|goods|items|merchandise|solutions}, drug molecules and peptides with {excellent|superb|outstanding|exceptional|great|fantastic} chemoselectivity. 2089377-51-3 Chemscene 2,3-Dihydroxyterephthalic acid In stock PMID:23613863
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