The synthesis of medicinally relevant α-difluoroalkylated amines by an iridium-catalyzed reductive alkylation of tertiary amides and lactams with difluoro-Reformatsky reagents, is described. This report {features|attributes|functions|characteristics|capabilities|options} the introduction of {various|numerous|different|a variety of|several|many} geminal difluoro-acetates and -acetamides {as well|also|too|at the same time} as late stage derivatization of APIs, gram scale synthesis and downstream functionalizations. Price of 6-Bromochroman-4-amine Formula of Zinc(II) difluoromethanesulfinate PMID:34235739
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