Polymers that release functional {small|little|tiny|modest|smaller|compact} molecules {under|below|beneath} mechanical {stress|tension|anxiety|pressure|strain} potentially serve as next-generation {materials|supplies|components} for catalysis, sensing, and mechanochemical dynamic therapy. To {further|additional} expand the function of mechanoresponsive {materials|supplies|components}, the discovery of chemistries capable of {small|little|tiny|modest|smaller|compact} molecule release are {highly|extremely|very|hugely} desirable. {In this|Within this} report, we detail a non-scissile bifunctional mechanophore (i.e., dual mechano-activated properties) {based|primarily based} on a {unique|distinctive|special|exclusive|exceptional|one of a kind} mechanochemical reaction involving norborn-2-en-7-one (NEO). {One|1|A single|One particular} {property|home|house} {is the|will be the|may be the|would be the|could be the|is definitely the} release of carbon monoxide (CO) upon pulsed {solution|answer|remedy|resolution|option} ultrasonication. A release efficiency of 58% is observed at {high|higher} molecular weights (Mn = 158.{8|eight} kDa), equating to ~154 molecules of CO re-leased per chain. The second {property|home|house} {is the|will be the|may be the|would be the|could be the|is definitely the} {bright|vibrant} cyan emission {from the|in the} macromolecular {product|item|solution} in its aggregated state, resulting {in a|inside a|within a} turn-on fluorescence readout coincident with CO release. This report {not only|not just|not merely|not simply} demonstrates a {unique|distinctive|special|exclusive|exceptional|one of a kind} {strategy|technique|method|approach|tactic} for the release of {small|little|tiny|modest|smaller|compact} molecule {in a|inside a|within a} non-scissile way, {but also|but additionally|but in addition} guides future {design|style|design and style} of force-responsive aggregation-induced emission (AIE) luminogens. Price of 3-Formyl-1H-indazole-5-carboxylic acid Br-PEG3-C2-Boc Purity PMID:23812309
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