Dynamical diffraction effects {are usually|are often} {considered|regarded as|deemed|regarded|viewed as|thought of} a nuisance for structure {analysis|evaluation} from continuous-rotation 3D electron diffraction (3D ED) {data|information} like cRED and MicroED. {Here|Right here} we demonstrate that by accounting for these effects {during the|throughout the|through the} structure refinement, {significantly|considerably|substantially|drastically} {improved|enhanced} models {can be|may be|could be|might be|is often|is usually} obtained {in terms of|when it comes to|with regards to} accuracy and reliability with {up to|as much as} four-fold reduction {of the|from the|in the|on the|with the|of your} noise level in {difference|distinction} Fourier maps in comparison {to the|towards the|for the} {standard|regular|normal|common|typical} structure determination routines that ignore dynamical diffraction. As dynamical diffraction effects break the inversion symmetry {of the|from the|in the|on the|with the|of your} diffraction, they {allow|permit|enable|let} a {quick|fast|rapid|swift|speedy}, {easy|simple|straightforward|effortless|uncomplicated|quick}, and {reliable|dependable|trustworthy|reputable|trusted} determination {of the|from the|in the|on the|with the|of your} absolute structure of chiral crystals. Formula of 102045-96-5 Formula of 2-Bromo-5-chlorotoluene PMID:31085260
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