{Specific|Particular|Certain|Distinct|Precise} bioconjugation for native {primary|main|major|principal|key} amines is {highly|extremely|very|hugely} {valuable|beneficial|useful|worthwhile|precious|important} for {both|each} chemistry and biomedical {research|study|analysis|investigation}. {Despite|Regardless of|In spite of} {all the|all of the|each of the} efforts, scientists lack a {proper|correct|appropriate|suitable|right} {strategy|technique|method|approach|tactic} {to achieve|to attain} {high|higher} selectivity for {primary|main|major|principal|key} amines, {not to|to not} mention the requirement of {fast|quick|quickly|rapidly|rapid|speedy} response for {real|genuine|actual|true} applications. Herein, {in this|within this} {work|function|perform|operate}, we report a chromone-based aggregation-induced emission (AIE) fluorogen {called|known as|referred to as|named} CMVMN as a self-reporting bioconjugation reagent for selective {primary|main|major|principal|key} amine identification, and its applications for monitoring bioprocesses of amination and protein labeling. CMVMN is AIE-active and is capable of solid-state sensing. {Thus|Therefore|Hence|As a result}, its electrospun films are manufactured for visualization of amine diffusion and leakage {process|procedure|method|approach|course of action}. CMVMN also shows {good|great|excellent|very good|fantastic|superior} biocompatibility and {potential|possible|prospective} mitochondria-staining {ability|capability|capacity|potential}, which {provides|offers|gives|supplies|delivers} new insight for organelle-staining probe {design|style|design and style}. Combined with its facile synthesis and {good|great|excellent|very good|fantastic|superior} reversibility, CMVMN {not only|not just|not merely|not simply} shows wide {potential|possible|prospective} applications in biology, {but also|but additionally|but in addition} {offers|provides|gives|delivers|presents} new possibilities for molecular engineering. Biotin-PEG1-NH2 Price 3-Methoxy-4-pyridinamine Order PMID:23453497
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