The Periodic Table as a Cultural Meme
The Mendeleev periodic table is 150 years old this year. {This article|This short article} {looks|appears} at how it has changed in its history and its wider recognition in human society.…
Olefin Metathesis in Confinement: Towards Covalent Organic Framework Scaffolds for {Increased|Elevated|Improved|Enhanced} Macrocyclization Selectivity
Covalent organic frameworks (COFs) {offer|provide|supply|offer you|present|give} vast structural and chemical diversity enabling a wide and {growing|expanding|developing|increasing} {range|variety} of applications. {While|Whilst|Although|Even though|When|Though} COFs are well-established as homogeneous catalysts, so far, their…
An {efficient|effective} {way to|method to|approach to|strategy to|technique to|solution to} screen inhibitors of energy-coupling {factor|aspect|element|issue} (ECF) transporters in bacteria uptake assay
Herein, we report a novel whole-cell screening assay {using|utilizing|making use of|employing|working with|applying} Lactobacillus casei as model microorganism to {identify|determine|recognize} inhibitors of energy-coupling {factor|aspect|element|issue} (ECF) transporters. This promising and underexplored target…
Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with {High|Higher} Drug-to-Antibody Ratios
The {potential|possible|prospective} of antibody conjugates with {high|higher} drug loading in anticancer therapy has {recently|lately|not too long ago} been highlighted by the approval of Trastuzumab deruxtecan and Sacituzumab govitecan. These biopharmaceutical…
Iron(IV) Complexes with Tetraazaadamantane-based Ligands: Synthesis, Structure, Application in Dioxygen Activation and Labeling of Biomolecules
{4|four},{6|six},10-Trihydroxy-1,{4|four},{6|six},10-tetraazaadamantane (TAAD) has been shown to {form|type|kind} a {stable|steady} Fe(IV) {complex|complicated} {having|getting|possessing|obtaining} a diamantane cage structure, in which the metal center is coordinated by {three|3} oxygen atoms {of the|from the|in…
ChemSpaX: Exploration of Chemical Space by Automated Functionalization of Molecular Scaffold
Exploration {of the|from the|in the|on the|with the|of your} {local|nearby|neighborhood|regional} chemical space of molecular scaffolds by post-functionalization (PF) {is a|is really a|is actually a|can be a|is often a|is usually a} promising…
Pattern Recognition of microRNA Expression in {Body|Physique} Fluids {using|utilizing|making use of|employing|working with|applying} Nanopore Decoding at Sub-femtomolar Concentration
This paper describes nanopore decoding for microRNA (miRNA) expression patterns {using|utilizing|making use of|employing|working with|applying} DNA computing {technology|technologies}. miRNAs have shown {promise|guarantee} as markers for cancer diagnosis {due to|because of|as a…
Kinetic Probes {of the|from the|in the|on the|with the|of your} Origin of Activity in MOF-Based C–H Oxidation Catalysts
The {development|improvement} of homogeneous catalysis is enabled by the availability of a {rich|wealthy} toolkit of kinetics experiments, {such as|like|including|for example|for instance|which include} the Hg-drop test, that differentiate catalytic activity at…
Electronic Structure Benchmark Calculations of Inorganic and Biochemical Carboxylation Reactions
Carboxylation reactions represent {a very|a really|an extremely|an incredibly} {special|unique|particular|specific} class of chemical reactions {that is|that’s|which is|that is certainly|that is definitely|that may be} characterized by the presence of a carbon dioxide…
A Database of Low-Energy Atomically Precise Nanoclusters
The chemical and structural properties of atomically precise nanoclusters are of {great|fantastic|excellent|wonderful|good|terrific} interest in {numerous|many|several|quite a few|a lot of|various} applications, {but the|however the} structures {of the|from the|in the|on the|with the|of…