Cell-to-cell signaling, or quorum sensing (QS), in Gram-negative bacteria is governed by {small|little|tiny|modest|smaller|compact} molecule signals (N-acyl L-homoserine lactones, AHLs) and their cognate intracellular receptors (LuxR-type proteins). The mechanistic underpinnings of…
N-functionalized aziridines, {which are|that are} {both|each} {useful|helpful|beneficial|valuable} intermediates and are present in {important|essential|crucial|critical|significant|vital} synthetic targets, {can be|may be|could be|might be|is often|is usually} envisioned as arising {from the|in the} direct addition…
Methicillin-resistant Staphylococcus aureus (MRSA) {is a|is really a|is actually a|can be a|is often a|is usually a} {major|significant|main|key|big|important} threat to human {health|well being|wellness|overall health}, {as the|because the} US mortality {rate|price} outweighs…
This paper reports {on the|around the} {first|initial|very first|1st|initially} ab initio molecular dynamics study {of the|from the|in the|on the|with the|of your} ferroelectric Sodium Nitrite, shedding light on its order-disorder phase transition.…
Chemical probes are {valuable|beneficial|useful|worthwhile|precious|important} tools to {explore|discover} the function of proteins. Incorporation of electrophiles into {small|little|tiny|modest|smaller|compact} molecules enables covalent capture of protein interactions and {provides|offers|gives|supplies|delivers} access to {powerful|potent|effective|strong|highly effective} technologies…
We introduce a {strategy|technique|method|approach|tactic} for the fluorogenic and genetic targeting of a calcium sensor by combining a protein fluorogen {with the|using the|with all the|together with the} BAPTA sensing group. The…
{In this|Within this} proof-of-principle study, we present our contribution to single particle inductively coupled plasma mass spectrometry (spICPMS) developments {with a|having a|using a} novel in-house {built|constructed} {data|information} acquisition {system|method|program|technique} with…
Computer-assisted {design|style|design and style} of {small|little|tiny|modest|smaller|compact} molecules has {experienced|skilled|knowledgeable|seasoned} a resurgence in academic and indus-trial interest {due to|because of|as a result of|on account of|resulting from|as a consequence of} the widespread…
Thermal density functional theory is {commonly|generally|typically|frequently|normally|usually} {used|utilized|employed|utilised|applied|made use of} in simulations of warm dense matter, a {highly|extremely|very|hugely} energetic phase characterized by substantial thermal effects and by correlated electrons demanding quantum…
The host-guest doped {strategy|technique|method|approach|tactic} has been {widely|extensively|broadly} recognized as {an effective|an efficient} {method|technique|approach|strategy|system|process} to construct {room|space|area} temperature phosphorescence {materials|supplies|components}. {However|Nevertheless|Nonetheless|Even so|On the other hand|Having said that}, the {advantage|benefit} {of the|from…